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	<title>Comments on: Patrick Holford Shares His Wisdom in May 2008 Newsletter</title>
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	<link>http://holfordwatch.info/2008/05/16/patrick-holford-shares-his-wisdom-in-may-2008-newsletter/</link>
	<description>The truth about Patrick Holford, media nutritionist</description>
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		<title>By: Daily Record Promotes Nutritionism Nonsense: There Is A Patrick Holford Connection, Of Course &#171; Holford Watch: Patrick Holford, nutritionism and bad science</title>
		<link>http://holfordwatch.info/2008/05/16/patrick-holford-shares-his-wisdom-in-may-2008-newsletter/comment-page-1/#comment-13980</link>
		<dc:creator><![CDATA[Daily Record Promotes Nutritionism Nonsense: There Is A Patrick Holford Connection, Of Course &#171; Holford Watch: Patrick Holford, nutritionism and bad science]]></dc:creator>
		<pubDate>Fri, 02 Jan 2009 17:08:50 +0000</pubDate>
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		<description><![CDATA[[...] 100%health subscription service. Now, we&#8217;ve commented on the quality of this service on several occasions and questioned whether it represents value for money. However, in these times of repeated laments [...]]]></description>
		<content:encoded><![CDATA[<p>[...] 100%health subscription service. Now, we&#8217;ve commented on the quality of this service on several occasions and questioned whether it represents value for money. However, in these times of repeated laments [...]</p>
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		<title>By: Mary Parsons</title>
		<link>http://holfordwatch.info/2008/05/16/patrick-holford-shares-his-wisdom-in-may-2008-newsletter/comment-page-1/#comment-12044</link>
		<dc:creator><![CDATA[Mary Parsons]]></dc:creator>
		<pubDate>Tue, 23 Sep 2008 20:43:14 +0000</pubDate>
		<guid isPermaLink="false">http://holfordwatch.wordpress.com/?p=439#comment-12044</guid>
		<description><![CDATA[I thought I remembered you had discussed soy supplements and breast cancer. You might be interested in this study although it is a mouse model. &lt;a href=&quot;http://www.news.uiuc.edu/news/08/0923genistein.html&quot; rel=&quot;nofollow&quot;&gt;The dietary supplement genistein can undermine breast cancer treatment&lt;/a&gt;.
&lt;blockquote&gt;“To think that a dietary supplement could actually reverse the effects of a very effective drug is contrary to much of the perceived benefits of soy isoflavones, and unsettling,” said William Helferich a professor of food science and human nutrition at Illinois and principal investigator on the study. “You have women who are taking these supplements to ameliorate post-menopausal symptoms and assuming that they are as safe as consuming a calcium pill or a B vitamin.”

Many women take genistein supplements to control hot flashes and other symptoms of menopause. The researchers found that the doses commonly available in dietary supplements were potent enough to negate the effectiveness of aromatase inhibitors.
&lt;/blockquote&gt;
You know, this should disquiet anyone who says that &#039;natural products&#039; don&#039;t need to be tested because they are just commonsense.

Harriet Hall made a comment that highlights some &lt;a href=&quot;http://www.sciencebasedmedicine.org/?p=206#comment-8995&quot; rel=&quot;nofollow&quot;&gt;different standards in the comparison of drugs v. &#039;natural remedies&#039;&lt;/a&gt;.
&lt;blockquote&gt;Suppose you learned that a prescription drug you were taking had only been tested in preclinical trials on animals, but had never been tested on humans. Suppose an expert panel reviewed all the available data on this prescription drug and concluded that it was only “possibly” effective and “possibly” safe. Would you keep taking it? I think most people would stop taking it and would be very critical of the FDA for letting it on the market without proper testing.
&lt;/blockquote&gt;]]></description>
		<content:encoded><![CDATA[<p>I thought I remembered you had discussed soy supplements and breast cancer. You might be interested in this study although it is a mouse model. <a href="http://www.news.uiuc.edu/news/08/0923genistein.html" rel="nofollow">The dietary supplement genistein can undermine breast cancer treatment</a>.</p>
<blockquote><p>“To think that a dietary supplement could actually reverse the effects of a very effective drug is contrary to much of the perceived benefits of soy isoflavones, and unsettling,” said William Helferich a professor of food science and human nutrition at Illinois and principal investigator on the study. “You have women who are taking these supplements to ameliorate post-menopausal symptoms and assuming that they are as safe as consuming a calcium pill or a B vitamin.”</p>
<p>Many women take genistein supplements to control hot flashes and other symptoms of menopause. The researchers found that the doses commonly available in dietary supplements were potent enough to negate the effectiveness of aromatase inhibitors.
</p></blockquote>
<p>You know, this should disquiet anyone who says that &#8216;natural products&#8217; don&#8217;t need to be tested because they are just commonsense.</p>
<p>Harriet Hall made a comment that highlights some <a href="http://www.sciencebasedmedicine.org/?p=206#comment-8995" rel="nofollow">different standards in the comparison of drugs v. &#8216;natural remedies&#8217;</a>.</p>
<blockquote><p>Suppose you learned that a prescription drug you were taking had only been tested in preclinical trials on animals, but had never been tested on humans. Suppose an expert panel reviewed all the available data on this prescription drug and concluded that it was only “possibly” effective and “possibly” safe. Would you keep taking it? I think most people would stop taking it and would be very critical of the FDA for letting it on the market without proper testing.
</p></blockquote>
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		<title>By: Patrick Holford and Scientific Accuracy and Attention to Detail: He Needs It &#171; Holford Watch: Patrick Holford, nutritionism and bad science</title>
		<link>http://holfordwatch.info/2008/05/16/patrick-holford-shares-his-wisdom-in-may-2008-newsletter/comment-page-1/#comment-9718</link>
		<dc:creator><![CDATA[Patrick Holford and Scientific Accuracy and Attention to Detail: He Needs It &#171; Holford Watch: Patrick Holford, nutritionism and bad science]]></dc:creator>
		<pubDate>Sun, 18 May 2008 01:56:25 +0000</pubDate>
		<guid isPermaLink="false">http://holfordwatch.wordpress.com/?p=439#comment-9718</guid>
		<description><![CDATA[[...] at a later date, not least because it involves a special trip to a national library to look up some remarkably obscure resources. Because, cue the ominous music, no matter how much evidence you have for someone&#8217;s regular [...]]]></description>
		<content:encoded><![CDATA[<p>[...] at a later date, not least because it involves a special trip to a national library to look up some remarkably obscure resources. Because, cue the ominous music, no matter how much evidence you have for someone&#8217;s regular [...]</p>
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		<title>By: dvnutrix</title>
		<link>http://holfordwatch.info/2008/05/16/patrick-holford-shares-his-wisdom-in-may-2008-newsletter/comment-page-1/#comment-9710</link>
		<dc:creator><![CDATA[dvnutrix]]></dc:creator>
		<pubDate>Fri, 16 May 2008 21:44:02 +0000</pubDate>
		<guid isPermaLink="false">http://holfordwatch.wordpress.com/?p=439#comment-9710</guid>
		<description><![CDATA[And - yes. The antiquity and marginal nature of many of the favourite, frequently-used Holford references defies belief. I can&#039;t decide whether I especially like a reference to an obscure catering report from 1981 or a &lt;a href=&quot;http://books.google.co.uk/books?id=ElDY_DJn9CoC&amp;pg=PA540&amp;lpg=PA540&amp;dq=%22myth+of+the+balanced+diet%22+cassette&amp;source=web&amp;ots=2yy2gJ4uVg&amp;sig=Qgb2ck0XWqp6-FMkASgY7y_UcmY&amp;hl=en&quot; rel=&quot;nofollow&quot;&gt;no-longer-available cassette of a lecture delivered in 1993&lt;/a&gt; (in the leading-edge, up-dated &lt;i&gt;New Optimum Nutrition Bible&lt;/i&gt;: see refs 17 and 18, as Goldacre implies, it would be almost impossible to track these down).]]></description>
		<content:encoded><![CDATA[<p>And &#8211; yes. The antiquity and marginal nature of many of the favourite, frequently-used Holford references defies belief. I can&#8217;t decide whether I especially like a reference to an obscure catering report from 1981 or a <a href="http://books.google.co.uk/books?id=ElDY_DJn9CoC&amp;pg=PA540&amp;lpg=PA540&amp;dq=%22myth+of+the+balanced+diet%22+cassette&amp;source=web&amp;ots=2yy2gJ4uVg&amp;sig=Qgb2ck0XWqp6-FMkASgY7y_UcmY&amp;hl=en" rel="nofollow">no-longer-available cassette of a lecture delivered in 1993</a> (in the leading-edge, up-dated <i>New Optimum Nutrition Bible</i>: see refs 17 and 18, as Goldacre implies, it would be almost impossible to track these down).</p>
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		<title>By: dvnutrix</title>
		<link>http://holfordwatch.info/2008/05/16/patrick-holford-shares-his-wisdom-in-may-2008-newsletter/comment-page-1/#comment-9709</link>
		<dc:creator><![CDATA[dvnutrix]]></dc:creator>
		<pubDate>Fri, 16 May 2008 21:23:31 +0000</pubDate>
		<guid isPermaLink="false">http://holfordwatch.wordpress.com/?p=439#comment-9709</guid>
		<description><![CDATA[You know, Dr Aust - a while back, HW quoted &lt;a href=&quot;http://holfordwatch.info/2007/10/02/patrick-holford-the-poet-of-putney/&quot; rel=&quot;nofollow&quot;&gt;Patrick Holford&#039;s juvenilia&lt;/a&gt; in the form of this poem:
&lt;blockquote&gt;Nature always provides a solution,
To help us with our evolution.
It seems obvious to me,
We need vitamin C,
To combat excessive pollution.
[pg 92: The Whole Health Manual, 1981]
&lt;/blockquote&gt;
A couple of people wondered if it was appropriate to include something from so long ago - but we recently learned that Holford is proud enough of this piece that he had it included in his &lt;a href=&quot;http://www.thegmcgroup.com/item--Organic-Life-Issue-027-Jan-08--OL-027-018.html&quot; rel=&quot;nofollow&quot;&gt;Jan 2008 interview in &lt;i&gt;Organic Life&lt;/i&gt;&lt;/a&gt; (pp. 16-18 and 20).* So, he is obviously still heavily engaged with the marvels of the early 80s and maybe this study of 7 reminds him of those heady days.

*On the cover, he is the story: The Man Who Knows the Secret of Life. The hagiographer is Helen Vintner Eaton.]]></description>
		<content:encoded><![CDATA[<p>You know, Dr Aust &#8211; a while back, HW quoted <a href="http://holfordwatch.info/2007/10/02/patrick-holford-the-poet-of-putney/" rel="nofollow">Patrick Holford&#8217;s juvenilia</a> in the form of this poem:</p>
<blockquote><p>Nature always provides a solution,<br />
To help us with our evolution.<br />
It seems obvious to me,<br />
We need vitamin C,<br />
To combat excessive pollution.<br />
[pg 92: The Whole Health Manual, 1981]
</p></blockquote>
<p>A couple of people wondered if it was appropriate to include something from so long ago &#8211; but we recently learned that Holford is proud enough of this piece that he had it included in his <a href="http://www.thegmcgroup.com/item--Organic-Life-Issue-027-Jan-08--OL-027-018.html" rel="nofollow">Jan 2008 interview in <i>Organic Life</i></a> (pp. 16-18 and 20).* So, he is obviously still heavily engaged with the marvels of the early 80s and maybe this study of 7 reminds him of those heady days.</p>
<p>*On the cover, he is the story: The Man Who Knows the Secret of Life. The hagiographer is Helen Vintner Eaton.</p>
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		<title>By: Dr Aust</title>
		<link>http://holfordwatch.info/2008/05/16/patrick-holford-shares-his-wisdom-in-may-2008-newsletter/comment-page-1/#comment-9708</link>
		<dc:creator><![CDATA[Dr Aust]]></dc:creator>
		<pubDate>Fri, 16 May 2008 20:53:53 +0000</pubDate>
		<guid isPermaLink="false">http://holfordwatch.wordpress.com/?p=439#comment-9708</guid>
		<description><![CDATA[I would say that I can&#039;t believe the best PH can do is quote a 1982 study on seven subjects... ...except that it is only too believable, on previous form.

Isn&#039;t this one of the things Ben Goldacre argued was a hallmark of pseudoscience?  I mean citations of long-expired (and often unobtainable without a trek to a Univ library to get the paper version from the stacks) papers while ignoring all the far more comprehensive later work.

Cher Patrique truly is ...a  phenomenon.]]></description>
		<content:encoded><![CDATA[<p>I would say that I can&#8217;t believe the best PH can do is quote a 1982 study on seven subjects&#8230; &#8230;except that it is only too believable, on previous form.</p>
<p>Isn&#8217;t this one of the things Ben Goldacre argued was a hallmark of pseudoscience?  I mean citations of long-expired (and often unobtainable without a trek to a Univ library to get the paper version from the stacks) papers while ignoring all the far more comprehensive later work.</p>
<p>Cher Patrique truly is &#8230;a  phenomenon.</p>
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		<title>By: Dr Aust</title>
		<link>http://holfordwatch.info/2008/05/16/patrick-holford-shares-his-wisdom-in-may-2008-newsletter/comment-page-1/#comment-9707</link>
		<dc:creator><![CDATA[Dr Aust]]></dc:creator>
		<pubDate>Fri, 16 May 2008 20:50:06 +0000</pubDate>
		<guid isPermaLink="false">http://holfordwatch.wordpress.com/?p=439#comment-9707</guid>
		<description><![CDATA[Oops - something went wonky with the HTML then *sigh*. I do hate computers.

Edit: &lt;b&gt;Fixed - I think.&lt;/b&gt;]]></description>
		<content:encoded><![CDATA[<p>Oops &#8211; something went wonky with the HTML then *sigh*. I do hate computers.</p>
<p>Edit: <b>Fixed &#8211; I think.</b></p>
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		<title>By: Dr Aust</title>
		<link>http://holfordwatch.info/2008/05/16/patrick-holford-shares-his-wisdom-in-may-2008-newsletter/comment-page-1/#comment-9706</link>
		<dc:creator><![CDATA[Dr Aust]]></dc:creator>
		<pubDate>Fri, 16 May 2008 20:47:49 +0000</pubDate>
		<guid isPermaLink="false">http://holfordwatch.wordpress.com/?p=439#comment-9706</guid>
		<description><![CDATA[Of course, the technical term for images that &quot;code&quot; a difference in something un-colourful (like increased oxygenated blood flow as a consequence of increased regional brain activity, commonly expressed as a &lt;i&gt;greyscale&lt;/i&gt; image)  into nice bright hot colours is called: 

&lt;a href=&quot;http://en.wikipedia.org/wiki/False-color&quot; rel=&quot;nofollow&quot;&gt;
&quot;pseudocolour&quot;&lt;/a&gt;

- I wonder if it is the bright colours, or just  the pseudo-, that explains the mesmerising effect of such things on certain folk?]]></description>
		<content:encoded><![CDATA[<p>Of course, the technical term for images that &#8220;code&#8221; a difference in something un-colourful (like increased oxygenated blood flow as a consequence of increased regional brain activity, commonly expressed as a <i>greyscale</i> image)  into nice bright hot colours is called: </p>
<p><a href="http://en.wikipedia.org/wiki/False-color" rel="nofollow"><br />
&#8220;pseudocolour&#8221;</a></p>
<p>- I wonder if it is the bright colours, or just  the pseudo-, that explains the mesmerising effect of such things on certain folk?</p>
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