Tag Archives: CVD
Patrick Holford blogs cohort study which finds that “Multivitamin use was not related to total mortality”
I was interested to see Holford blogging about Pocobelli et al’s recent article on “Use of supplements of multivitamins, vitamin C, and vitamin E in relation to mortality”. Holford reports the study as finding that “Multivitamin use cuts heart disease … Continue reading
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Patrick Holford Claims More People Die, Prematurely, From Cardiovascular Disease Than Actually Die, Prematurely, From All Causes
Patrick Holford persists in exaggerating the number of premature deaths from cardiovascular disease by approx. 500%. He also claims that doctors are uninterested in diet and lifestyle interventions. We discuss his errors in some detail. Continue reading
Filed under Holford, home test, hometesting, homocysteine, patrick holford, supplements
Alternative Nutrition bingo: we predict industry responses to the JAMA trial of vitamin C and E
The Journal of the American Medical Association has recently published a good quality, placebo-controlled, randomised, double-blind trial looking at whether vitamin C and E supplementation can reduce cardiovascular events. It ran for 10 years, and included “14 641 US male … Continue reading
Filed under antioxidants, supplements, vitamin c, vitamins
Homocysteine: Really Not a Crystal Ball
Former Visiting Professor Patrick Holford of Teesside University frequently advocates that everyone should test their homocysteine levels and if it breaches his notion of what is high, they should take his recommended supplements to reduce those levels (at a cost of around £700-1000 pp pa). The findings from recent trials report that although vitamin supplements successfully reduce homocysteine levels, there is no strong evidence of related clinical benefits such as a reduction in major cardiovascular events. Continue reading
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Polypills or Vitamins for Homocysteine and Cardiovascular Risks: the Hype is Ahead of the Evidence
There is renewed interest in the benefits of polypills for the over-55s. The claim is that each of the proposed components of this combination pill has already been clinically validated so it would only require small-scale trials to validate that it behaves in the same way so this product may come to market quite quickly. One of the components is folic acid to reduce homocysteine (Hcy) levels. However, the findings from recent trials concerned with primary prevention report that although vitamin supplements successfully reduce Hcy levels, there is no strong evidence of related clinical benefits such as a reduction in major cardiovascular events. Continue reading
Filed under Holford, homocysteine, patrick holford, supplements, vitamins
